Drug Standards
Medchemexpress LLC Neriifolin | 466-07-9 | MFCD00869436 | 1 ML
Neriifolin is a CNS-penetrating cardiac glycoside and an inhibitor of Na+, K+-ATPase. It targets beclin 1, which inhibits the formation of LC3-associated phagosomes and helps to ameliorate the development of experimental autoimmune encephalomyelitis (EAE). Additionally, Neriifolin can induce cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
- Targets Atg8/LC3, Na+/K+ ATPase, Apoptosis, Beclin1
- Used in cardiovascular disease research
- Used in inflammation/immunology research
- Used in cancer research
- Inhibits the formation of LC3-associated phagosomes
- Ameliorates experimental autoimmune encephalomyelitis development
- Induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells
Medchemexpress LLC Metoprolol (succinate) (standard) | 98418-47-4 | MFCD23115896 | 99.8% | 652.82 | C34H56N2O10 | 10 MG
Metoprolol succinate (standard) is an analytical reference standard of the succinate salt of metoprolol, a selective β1-adrenoceptor antagonist. It is intended for research and analytical use, including method development, assay validation, and quality control in laboratory settings.
- High purity suitable for analytical use (assay 99.82%).
- Provided as a stable solid in amber/brown glass packaging.
- Molecular formula C34H56N2O10 and molecular weight 652.82.
- CAS number 98418-47-4 for unambiguous identification.
- Suitable for method development, assay calibration, and quality control.
TARGETMOL CHEMICALS INC OPROZOMIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Oprozomib (PR-047) (ONX 0912) an inhibitor for CT-L activity of 20S proteasome (beta)5(IC50=36 nM)/LMP7(IC50=82 nM) is orally bioavailable. Oprozomib also has potential antineoplastic activity. purity: 99%
U.S. Pharmacopeia L-Methionine, 63-68-3, MFCD00063097, 200mg
Molecular formula C5-H11-N-O2-S, Molecular weight 149.21 g/mol, Melting Point 536 - 550.4 °F (280 - 288 °C), Boiling Point 366.8 °F (186 °C)
Medchemexpress LLC Isoprenaline hydrochloride | 51-30-9 | 99.86% | 5 G
Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. It possesses potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. It can be utilized for research pertaining to bradycardia and bronchial asthma.
- Non-selective β-adrenergic receptor agonist
- Potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities
- Utilized for research related to bradycardia and bronchial asthma
- Increases particulate cGMP- and cilostamide-inhibited, low-Km cAMP phosphodiesterase activity
- Inhibits insulin-stimulated glucose transport activity in rat adipocytes
- Increases cyclic AMP levels
- Increases the transcriptional activity of the Gi alpha-2 gene
Medchemexpress LLC Lenalidomide 5'-piperazine hydrochloride | 2222120-31-0 | 99.9% | 364.83 | C17H21ClN4O3 | 50 MG
Lenalidomide 5'-piperazine hydrochloride is a research-grade cereblon (CRBN) ligand used in chemical biology and degrader (PROTAC) development. It provides a piperazine-functionalized handle for linker attachment and is supplied as a hydrochloride salt for research use only.
Medchemexpress LLC Rebamipide impurity 13 | 4876-17-9 | MFCD22194962 | >98.0% | 193.63 g/mol | C10H8ClNO | 5 MG
Rebamipide impurity 13 is a small-molecule impurity derived from the gastroprotective agent rebamipide, supplied for research and drug-intermediate uses. It is characterized by a chloroquinolinone core and is used in analytical impurity profiling and as a synthetic intermediate in medicinal chemistry research.
- CAS number 4876-17-9.
- Molecular formula C10H8ClNO; molecular weight 193.63 g/mol.
- Commonly reported ≥98.0% purity by distributor specifications.
- Intended use drug intermediate and impurity reference in analytical studies.
- Storage recommendations: powder at -20°C or 4°C; solutions at -80°C or -20°C.
- Available in small research sizes such as 5 mg and 10 mg.
U.S. Pharmacopeia Sodium citrate dihydrate | 6132-04-3 | 294.10 g/mol | 1G
Sodium citrate dihydrate | 6132-04-3 | 294.10 g/mol | 1G
U.S. Pharmacopeia Phenylephrine Related Compound F, 1007885-60-0, MFCD29472421, 30mg
Molecular formula C10H13NO2.HCl.H20, Molecular weight 233.7, Melting point/freezing point 458.6 - 462.2 °F (237 - 239 °C), Chemical name: (R)-2-methyl-1,2,3,4-tetrahydroisoquinoline-4,8-diol hydrochloride hydrate
AdipoGen Paclitaxel,Chemical. CAS: 33069-62-4
Paclitaxel, AdipoGen Life Sciences. Chemical. CAS: 33069-62-4. Formula: C47H51NO14. MW: 853.9. Isolated from the bark of the pacific yew tree (Taxus brevifolia). Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase. Apoptosis inducer through aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK). Immunosuppressor. Immunostimulant. Antiproliferative agent for the prevention of restenosis. TRAIL sensitizer 33069-62-4
Medchemexpress LLC Detomidine (hydrochloride) | 90038-01-0 | 99.83% | 25 MG
Detomidine hydrochloride is an imidazole derivative and a potent α2-adrenergic agonist, demonstrating dose-dependent analgesic effects. It is intended for research use only and its use is currently licensed for horses. This compound produces pain-relieving effects by activating α2 catecholamine receptors, which reduces the production of excitatory neurotransmitters. Additionally, it affects cardiac and respiratory systems and exhibits antidiuretic action due to its inhibition of the sympathetic nervous system.
- Potent α2-adrenergic agonist
- Produces dose-dependent analgesic effects
- Intended for research use only
- Licensed for use in horses
- Activates α2 catecholamine receptors
- Reduces excitatory neurotransmitters
- Affects cardiac and respiratory systems
- Exhibits antidiuretic action
Medchemexpress LLC Ticagrelor impurity 5 | 1863036-49-0 | >99.5% | 578.63 g/mol | C26H32F2N6O5S | 10 MG
Ticagrelor impurity 5 is an analytical standard used as an impurity reference for ticagrelor. It is provided for research and analytical applications including impurity profiling, method development, and quality control. The compound has molecular formula C26H32F2N6O5S and a molecular weight of 578.63 g/mol.
- Analytical standard for impurity profiling and method development
- High reported purity (>99.5%) suitable for HPLC and MS reference
- Molecular formula C26H32F2N6O5S; molecular weight 578.63 g/mol
- Suitable for identity confirmation and chromatographic reference materials
- Recommended storage: solid at 4°C; in solvent under nitrogen at -80°C up to 6 months
Medchemexpress LLC Ketorolac | 74103-06-3 | 50 MG
Ketorolac (Standard) is the analytical standard of Ketorolac. It is a non-steroidal anti-inflammatory drug (NSAID) that acts as a nonselective COX inhibitor. It has IC50s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used in a 0.5% ophthalmic solution for research into allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Additionally, Ketorolac tromethamine is a DDX3 inhibitor and has potential for cancer research.
- Analytical standard for Ketorolac
- Non-steroidal anti-inflammatory drug (NSAID)
- Acts as a nonselective COX inhibitor
- Potential for research into allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain
- Functions as a DDX3 inhibitor with potential for cancer research
- Intended for research and analytical applications
Medchemexpress LLC Zileuton sodium | 118569-21-4 | 98.0% | C11H11N2NaO2S | 100 MG
Zileuton sodium is a potent and selective inhibitor of 5-lipoxygenase, exhibiting inflammatory activities.
- Potent and selective inhibitor of 5-lipoxygenase.
- Exhibits inflammatory activities.
- Reduces IL-2 levels by inhibiting 5-lipoxygenase.
- Decreases NF-κB expression and apoptotic index in I/R rats.
- Inhibits polyp formation in APCΔ468 colon and small intestine in rats, and increases apoptosis rates in polyps.