Drug Standards
Apexbio Technology LLC Fosaprepitant dimeglumine salt, 10mg. Cas: 265121-04-8 MFCD: MFCD23102059. Neurokinin-1 antagonist
Fosaprepitant dimeglumine salt (L-758,298 MK-0517) is an antagonist of neurokinin-1. 265121-04-8. MFCD23102059
Medchemexpress LLC Diltiazem hydrochloride | 33286-22-5 | 99.5% | 450.98 | 1 G
Diltiazem hydrochloride is identified as a Ca2+ influx inhibitor, also known as a slow channel blocker or calcium antagonist.
- Interacts with transmembrane segments IIIS6 and IVS6 in the α1 subunit of L-type Ca2+ channels.
- Causes a dose-dependent inhibition of contractions and Ca2+ influx stimulated by alpha adrenoceptor activation and high-K+ depolarization.
- Inhibits the Na-dependent Ca-efflux from heart mitochondria.
- Produces noncompetitive inhibition of Ca2+-induced contractions of depolarized rabbit aorta.
- Improves cardiac microcirculation and function in an experimental model of hyperthyroidism in rats.
- Reduces the percentage of fibrosis areas in the left ventricle in hyperthyroid rats.
- Decreases blood pressure and increases heart rate in spontaneously hypertensive rats (SHR).
Cayman Chemical Melengestrol Acetate 100mg
A synthetic progestogen; binds to progesterone receptors in rhesus monkey myometrial cytosolic preparations with high affinity relative to progesterone; suppresses estrus in rats at 0.1 mg/animal per day; reduces tumor growth in androgen-dependent and -independent prostate tumors in rats at 10 mg/kg
![Medchemexpress LLC (S)-5-tert-butyl 6-methyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate | 1129634-43-0 | MFCD29042197 | 100mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000266103.png-250.jpg)
Medchemexpress LLC (S)-5-tert-butyl 6-methyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate | 1129634-43-0 | MFCD29042197 | 100mg
Ledipasvir impurity 53 is an impurity of Ledipasvir (HY-15602)
Medchemexpress LLC Nitisinone | 104206-65-7 | 99.9% | 50 MG
Nitisinone is an orally active, competitive, and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. It promotes tyrosine accumulation in a dose-dependent manner and is used in studies of hereditary tyrosinemia type 1 (HT-1), a rare genetic disorder, and albinism.
- Orally active, competitive, and reversible 4-HPPD inhibitor
- Promotes tyrosine accumulation
- Used in studies of hereditary tyrosinemia type 1 (HT-1) and albinism
- Exhibits antiproliferative activity against various cell lines (HCT-116, HUVEC, L02, MC-38)
- Increases pigmentation in irides and new hair growth in albinism mouse models
Sigma Aldrich Fine Chemicals Biosciences Azathioprine Related Compound G United States Pharmacopeia (USP) Reference Standard | 5581-52-2 | 15MG
Azathioprine Related Compound G United States Pharmacopeia (USP) Reference Standard | Mol Wt: 292.28 | 5581-52-2 | 15MG
Apexbio Technology LLC Rizatriptan Benzoate 145202-66-0 10mg
Rizatriptan Benzoate (CAS 145202-66-0) is a synthetic small molecule structurally related to tryptamine that acts as a selective agonist at serotonin 5-HT1D receptors By targeting these G protein-coupled receptors Rizatriptan Benzoate modulates the release of vasoactive neuropeptides and inhibits neurogenic inflammation and vasodilation associated with cranial blood vessels This pharmacological profile has made it a valuable tool for investigating serotonergic signaling pathways receptor pharmacodynamics and migraine pathophysiology in preclinical research settings
Selleck Chemical LLC Rizatriptan Benzoate 10mg 145202-66-0 MK-462 Benzoate
Rizatriptan Benzoate (MK-462) is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Rivaroxaban impurity 68 | 845729-41-1 | 99.9% | C10H10N2O4 | 500 MG
Rivaroxaban impurity 68 is a chemical compound with the formula C10H10N2O4, used as a reference standard in research and quality control applications. It has a purity of 99.89% and a CAS number of 845729-41-1. This high-purity impurity is essential for identifying and quantifying impurities in Rivaroxaban formulations.
- High purity for accurate analytical results
- Essential for pharmaceutical quality control
- Ideal for research and development
- Reliable reference standard
Sigma Aldrich Fine Chemicals Biosciences Metaxalone Related Compound C United States Pharmacopeia (USP) Reference Standard | 805972-34-3 | 25MG
Metaxalone Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 373.49 | 805972-34-3 | 25MG
Medchemexpress LLC Haloperidol decanoate | 74050-97-8 | MFCD00866706 | 99.7% | 530.11 | C31H41ClFNO3 | 25 MG
Haloperidol decanoate is the decanoate ester of haloperidol, provided as a research reagent for studies of antipsychotic pharmacology and dopamine receptor activity. It is formulated as a long-acting depot ester commonly used in in vivo and analytical investigations of sustained antipsychotic effects.
- Long-acting depot ester for antipsychotic pharmacology studies.
- High purity suitable for analytical and in vivo research (reported ~99.7%).
- Molecular formula C31H41ClFNO3 and molecular weight 530.11 for accurate dosing and calculation.
- Available in small mg pack sizes convenient for research workflows.
Medchemexpress LLC Idoxuridine | 54-42-2 | 99.8% | 1 ML
Idoxuridine is an iodinated thymidine analogue that acts as a competitive inhibitor of phosphorylases. It inhibits viral activity, particularly viral eye infections like herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. It demonstrates an IC50 value of 4.3 μM against feline herpesvirus and shows anti-orthopoxvirus activity.
- Inhibits viral activity
- Acts as a competitive inhibitor of phosphorylases
- Inhibits DNA polymerase
- Affects viral replication
- Shows anti-orthopoxvirus activity
Medchemexpress LLC Iopamidol | 60166-93-0 | 99.9% | 50 MG
Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) suitable for various diagnostic applications. It contains amide and hydroxyl functionalities that can be utilized for generating chemical exchange saturation transfer (CEST) contrast. This product is for research use only.
- Nonionic, X-Ray iodinated contrast agent
- Suitable for a wide variety of diagnostic applications
- Amide and hydroxyl functionalities can be exploited for generating chemical exchange saturation transfer (CEST) contrast
- Can be used as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys in vivo
Medchemexpress LLC Glycopyrrolate | 596-51-0 | 99.9% | 398.33 | 5 MG
Glycopyrrolate (Glycopyrronium bromide) is a quaternary ammonium derivative and a muscarinic receptor antagonist. It has a bronchoprotective effect and positively influences blood pressure. It is used in research for bronchial diseases.
- Muscarinic receptor antagonist
- Bronchoprotective effect
- Beneficial effect on blood pressure
- Used for research of bronchial diseases
Medchemexpress LLC Latanoprost acid | 41639-83-2 | 95.1% | 390.51 | 10 MG
Latanoprost acid, an analog of prostaglandin (PG) F2α, is a selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. It inhibits RANKL-induced osteoclastogenesis and function by inhibiting the ERK, AKT, JNK, and p38 cascade, followed by the c-fos/NFATc1 pathway. Latanoprost acid is also a medication used to lower pressure inside the eyes.
- Selective prostanoid receptor (FP) agonist.
- Activates the FP-PG receptor.
- Inhibits RANKL-induced osteoclastogenesis and function.
- Lowers pressure inside the eyes.
- Inhibits ERK, AKT, JNK, and p38 cascade.
- Reduces protein expressions of c-fos and NFATc1 in bone marrow-derived macrophages cells (BMMs).
- Significantly inhibits mature osteoclast formation.
- Notably prevents LPS-induced bone destruction in 8-week-old C57BL/6J mice.